INTOXICATE

Which Poisoned Patients Need the ICU?

Background.

1. Fraction of poisoned patients each year admitted to ICU/Stepdown
2. Physiology of poisoning means that scoring systems meant to determine general illness like APACHE may not work.
3. X previously developed INTOXICATE with methods that had results.

Project Roadmap

graph LR
    A[Replicate Study in US] --> B[Refine Predictors] & C[Extend to Childrens]
    B --> D[Prospectively Validate]
    B --> E[Prospectively Validate]

(Brandenburg et al., 2017) Developed INTOXICATE to determine which poisoned patients need admission to the ICU/Stepdown unit. Below is the model. SBPS refers to systolic blood pressure. EMV refers to the Glasgow Coma Scale (eye, motor, verbal).

And after bort.

References

1. 1.Brandenburg, R. et al. The need for ICU admission in intoxicated patients: a prediction model. Clinical toxicology 55, 4–11 (2017).