Michael Chary, MD, PhD is an emergency physician, medical toxicologist, and physician-scientist whose work focuses on using computational methods to improve the detection, triage, and management of poisoning, substance use disorders, and other acute public health problems.
His research combines medical toxicology, emergency medicine, clinical informatics, natural language processing, and digital health.
Medical toxicology is the study of poisoning, adverse drug effects, substance use, medication interactions, and environmental or occupational exposures.
Dr. Chary’s toxicology work focuses on identifying clinically meaningful signals from complex sources of information, including poison center data, electronic health records, and online commentary.
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Emergency departments are a major point of care for patients with acute poisoning, overdose, intoxication, withdrawal, and complications of substance use.
Dr. Chary’s emergency medicine research focuses on how clinical workflows, decision support tools, and triage systems can improve patient care and resource use.
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Dr. Chary studies substance use disorders through both clinical and computational approaches, with an emphasis on opioid withdrawal, polysubstance use, and emerging substances discussed in online communities.
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Computational toxicology uses data science, machine learning, and natural language processing to identify patterns in toxicologic exposures and outcomes.
Dr. Chary’s work includes developing pipelines to extract substances, symptoms, effects, and treatment claims from unstructured text.
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Online communities contain real-world descriptions of drug effects, supplement use, adverse reactions, withdrawal experiences, and self-treatment strategies.
Dr. Chary studies how these data can be used responsibly to identify emerging toxicologic and public health signals.
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Clinical decision support tools can help clinicians identify which poisoned patients need intensive monitoring, antidotal therapy, or higher levels of care.
Dr. Chary’s work examines how such tools are developed, validated, implemented, and adopted in real clinical settings.
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Poison control centers and digital triage tools are central to the management of poisoning in the United States.
Dr. Chary’s research examines how telephone-based, web-based, and hospital-based toxicology systems interact, and how digital tools may improve access to safe toxicologic guidance.
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Dr. Chary’s broader digital health work focuses on building tools that convert messy real-world data into clinically useful information.
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